KMID : 0545120090190091065
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Journal of Microbiology and Biotechnology 2009 Volume.19 No. 9 p.1065 ~ p.1069
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Investigation of Klebsiella pneumoniae Isolates Producing SHV-12 and SHV-11 ¥â-Lactamases in Korean Hospitals
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Lee Kyeong-Min
Yoo Jae-Il Yoo Yong-Sun Yoo Jung-Sik Chung Gyung-Tae Ahn Tae-In Lee Yeong-Seon
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Abstract
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Of 143 clinical isolates of Klebsiella pneumoniae collected from Korean non-tertiary hospitals, 24 (16.8%) showed an extended-spectrum ¥â-lactamase-positive phenotype. PCR and sequence analysis revealed the presence of TEM-116 (n=13), CTX-M-3 (n=5), CTX-M-14 (n=2), CTX-M-15 (n=3), and SHV-12 (n=16). Each of the 24 isolates encoded more than one ¥â-lactamase, and seven isolates (29%) harbored two different SHV-type ¥â-lactamase genes (blaSHV-11 and blaSHV-12) bounded by insertion sequence IS26 in a single transferable plasmid.
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KEYWORD
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Klebsiella pneumoniae, SHV-11, SHV-12, extended spectrum ¥â-lactamase
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